Study on manufacture of nifedipine microspherules with prolonged action
- Author:
Hue minh Pham
- Publication Type:Journal Article
- Keywords:
nifedipine
- MeSH:
Nifedipine;
Microspheres
- From:Pharmaceutical Journal
2001;298(2):17-19
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
Nifedifine was incorporated in ethyl cellulose microspheres using the solvent evaporation process. The effects of the EC concentrations, the methylene chloride volumes and the stirring rates on the drug release from microspheres were studied. The dissolution profile of a microsphere formulation was found to be similar to that of adalat retard by the optimization method and the statistical analysis. This formulation may be useful in a nifedipine sustained release dosage form
