Exploring factors affecting activities of daily living in patients with osteoporotic vertebral fractures managed conservatively: a post-hoc analysis of a prospective cohort study
- Author:
Toru FUNAYAMA
1
;
Masaki TATSUMURA
;
Kengo FUJII
;
Yosuke SHIBAO
;
Shun OKUWAKI
;
Kotaro SAKASHITA
;
Takahiro SUNAMI
;
Kento INOMATA
;
Hisanori GAMADA
;
Kousei MIURA
;
Hiroshi NOGUCHI
;
Hiroshi TAKAHASHI
;
Masao KODA
;
Masashi YAMAZAKI
Author Information
- Publication Type:Clinical Study
- From:Asian Spine Journal 2024;18(4):570-578
- CountryRepublic of Korea
- Language:English
-
Abstract:
Methods:A total of 224 consecutive patients with OVFs aged ≥65 years who received treatment within 2 weeks after the occurrence of injury were enrolled. The patients were followed up for 6 months thereafter. The criteria for evaluating the degree of independence were applied to evaluate ADLs. Multivariable analysis with a logistic regression model was performed to evaluate the risk factors for ADL decline.
Results:In total, 49/224 patients (21.9%) showed a decline in ADLs. Of these, 23/116 patients (19.8%) in the rest group and 26/108 patients (24.1%) in the no-rest group experienced a decline in ADLs. In the logistic regression analyses, a diffuse low signal on T2- weighted magnetic resonance imaging (MRI) (odds ratio, 5.78; 95% confidence interval, 2.09–16.0; p=0.0007) and vertebral instability (odds ratio, 3.89; 95% confidence interval, 1.32–11.4; p=0.0135) were identified as independent factors in the rest and no-rest groups, respectively.
Conclusions:In patients with acute OVFs, a diffuse low signal on T2-weighted MRI and severe vertebral instability were independently associated with ADL decline in patients treated with and without initial bed rest, respectively.
