Comparison of Age of Onset and Frequency of Diabetic Complications in the Very Elderly Patients with Type 2 Diabetes.
10.3803/EnM.2016.31.3.416
- Author:
Bong Ki LEE
1
;
Sang Wook KIM
;
Daehee CHOI
;
Eun Hee CHO
Author Information
1. Department of Internal Medicine, Kangwon National University School of Medicine, Chuncheon, Korea. ehcho@kangwon.ac.kr
- Publication Type:Original Article
- Keywords:
Diabetes;
Elderly;
Complication
- MeSH:
Age of Onset*;
Aged*;
Cerebral Infarction;
Creatinine;
Diabetes Complications*;
Diabetic Retinopathy;
Female;
Gangwon-do;
Hemoglobin A, Glycosylated;
Humans;
Incidence;
Male;
Medical Records;
Outpatients;
Prevalence
- From:Endocrinology and Metabolism
2016;31(3):416-423
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The prevalence of type 2 diabetes in elderly people has increased dramatically in the last few decades. This study was designed to clarify the clinical characteristics of type 2 diabetes in patients aged ≥80 years according to age of onset. METHODS: We reviewed the medical records of 289 patients aged ≥80 years with type 2 diabetes at the outpatient diabetes clinics of Kangwon National University Hospital from September 2010 to June 2014. We divided the patients into middle-age-onset diabetes (onset before 65 years of age) and elderly-onset diabetes (onset at 65+ years of age). RESULTS: There were 141 male and 148 female patients. The patients had a mean age of 83.2±2.9 years and the mean duration of diabetes was 14.3±10.4 years. One hundred and ninety-nine patients had elderly-onset diabetes. The patients with elderly-onset diabetes had a significantly lower frequency of diabetic retinopathy and nephropathy, lower serum creatinine levels, lower glycated hemoglobin (HbA1c) levels, and similar coronary revascularization and cerebral infarction rates compared to those with middle-age-onset diabetes. There was no frequency difference in coronary revascularization and cerebral infarction and HbA1c levels between three subgroups (<5, 5 to 15, and ≥15 years) of diabetes duration in elderly onset diabetes. However, both in the elderly onset diabetes and middle-age-onset diabetes, the cumulative incidence of retinopathy was increasing rapidly according to the duration of diabetes. CONCLUSION: We report that individuals with elderly-onset diabetes have a lower frequency of diabetic retinopathy and nephropathy and similar cardiovascular complications compared to those with middle-age-onset diabetes.
