Multimodal non-pharmacological interventions for Alzheimer's disease: a review

Author: ZHOU Ying ; LI Lian ; BIAN Guolin
Publication Type:Journal Article
Keywords: Alzheimer's disease; multimodal non-pharmacological interventions; cognitive function
From: Journal of Preventive Medicine 2024;36(12):1045-1048,1051
CountryChina
Language:Chinese
Abstract: Abstract:Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive dysfunction and behavioral impairments. Currently, the treatment mainly relies on pharmacotherapy, yet its effectiveness is limited and accompanied by adverse reactions. Multimodal non-pharmacological interventions (MNPI), which combine two or more non-pharmacological intervention approaches, can synergistically improve cognitive function, neuropsychiatric symptoms, activities of daily living, and quality of life in AD patients, and offers advantages of safety, cost-effectiveness and simplicity. This article reviews MNPI-related literature published domestically and internationally from 2018 to 2024, and focuses on the application of cognitive training, physical activity, and other combined intervention methods in MNPI, providing the reference for developing personalized interventions for AD.
Full text:2024121614523865673阿尔茨海默病多模式非药物干预的研究进展.pdf