Research Progress of Deinagkistrodon Acutus Venom
10.13748/j.cnki.issn1007-7693.20230099
- VernacularTitle:尖吻蝮蛇毒研究进展
- Author:
Chen YANG
1
,
2
;
Bin ZHANG
1
,
2
;
Caojuan CHEN
1
,
2
;
Pingan LIU
2
;
Yanmei PENG
2
;
Qunying TAN
3
;
Yuehui LI
1
,
2
Author Information
1. Hunan University of Traditional Chinese Medicine, Changsha 410208, China
2. Hunan Academy of Traditional Chinese Medicine, Changsha 410013, China
3. Hunan Yongzhou Yishe Biopharmaceutical Co., Ltd., Yongzhou 425000, China
- Publication Type:Review
- Keywords:
Deinagkistrodon acutus venom;
identify;
active ingredients;
toxicity study;
quality standard
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(23):3324-3333
- CountryChina
- Language:Chinese
-
Abstract:
Deinagkistrodon acutus(also known as the five-paced viper and the traditional Chinese medicine ingredient is called Agkistrodon) venom is a viscous liquid from the venom glands of the Deinagkistrodon acutus. It contains a variety of protein and peptide components such as phospholipase A2, serine protease, metalloproteinase, C-type lectin, L-amino acid oxidase, and has a variety of biological activities, playing an important role in anti-tumour, anti-thrombotic, anti-inflammatory and anti-bacterial activities. In recent years, snake venom research has become increasingly widespread, but there is still a lack of comprehensive and systematic studies on snake venom from Deinagkistrodon acutus. In this paper, the source, identification, active ingredients, toxicity studies and quality researches of Deinagkistrodon acutus venom are summarized and analysed by searching the related research progress, in order to provide reference for further development and utilization of Deinagkistrodon acutus venom.
