Research Progress on the Effect and Mechanism of Astragali Radix on Neurodegenerative Diseases
10.13748/j.cnki.issn1007-7693.20223585
- VernacularTitle:黄芪防治神经退行性疾病的作用及机制研究进展
- Author:
Ting PENG
1
;
Yuanyuan LIU
2
;
Xiaojie JIN
1
,
3
;
Yuefeng LI
1
,
3
;
Juan YAO
1
,
3
Author Information
1. Gansu University of Chinese Medicine, School of Pharmacy, Lanzhou 730000, China
2. Gansu University of Chinese Medicine, College of Basic Medical, Lanzhou 730000, China
3. Northwest Collaborative Innovation Center for Traditional Chinese Medicine Co-constructed by Gansu Province MOE of PRC, Lanzhou 730000, China
- Publication Type:Review
- Keywords:
Astragali Radix;
neuroprotection;
astragalus polysaccharides;
astragalus saponins;
research progress
- From:
Chinese Journal of Modern Applied Pharmacy
2023;40(23):3308-3317
- CountryChina
- Language:Chinese
-
Abstract:
As a kind of nervous system disease characterized by neuronal degeneration and death, neurodegenerative diseases pose a serious threat to human health. Due to its complex pathogenesis and poor therapeutic effect, neurodegenerative diseases have long attracted much attention. Modern studies have found that Astragali Radix has pharmacological effects such as cardiovascular and cerebrovascular protection, immune regulation, antioxidant and anti-aging, and its neuroprotective effect has been fully proved by a variety of scientific studies. This paper reviews the main pharmacological effects and mechanisms of commonly used Astragali Radix compounds and preparations and active ingredients of astragalus in the prevention and treatment of neurodegenerative diseases. In order to provide reference for the clinical application and basic research of Astragali Radix in neurodegenerative diseases.
