Discussion and treatment of late onset hypogonadism in male based on

Hui WU; Gang Ning; Bonan LI; Ajian Peng; Haoyu Wang; Ruobing Shi; Xing Zhou

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Discussion and treatment of late onset hypogonadism in male based on " tian gui out of time sequence"

VernacularTitle:基于“天癸失于时序”论治男性迟发性性腺功能减退症
Author: Hui WU ¹ ; Gang NING ¹ ; Bonan LI ² ; Ajian PENG ³ ; Haoyu WANG ³ ; Ruobing SHI ³ ; Xing ZHOU ³
Author Information

1. Graduate School of Hunan University of Chinese Medicine
2. The Fourth Hospital of Changsha
3. The First Hospital of Hunan University of Chinese Medicine
Publication Type:Journal Article
Keywords: tian gui; time sequence; late onset hypogonadism in male; testosterone
From: Journal of Beijing University of Traditional Chinese Medicine 2024;47(11):1501-1505
CountryChina
Language:Chinese
Abstract: The unique advantages of traditional Chinese medicine (TCM) in treating late onset hypogonadism in male have gradually emerged with the continuous deepening of the understanding and research on late onset hypogonadism in male. Time sequence is a general summary of the natural growth and operational laws. Tian gui and testosterone have their normal time sequences, and they may be associated with each other. A man′s tian gui follows the regular time sequence from " inception" to " exhaustion" throughout " eight" under normal physiological conditions. " Tian gui out of time sequence" includes the loss of tian gui exuberance (dysfunction of viscera dominated by the liver) and exhaustion in the time sequence (pathological deficiency of viscera dominated by the kidney), resulting in " tian gui exhaustion" in advance of " eight eight". Tian gui and testosterone are key concepts in Chinese and Western medicine for understanding late onset hypogonadism in male. The theory of " tian gui out of time sequence" may be closely related to the core pathogenesis of this condition, particularly in cases of liver depression and kidney deficiency. This study suggests that restoring the normal time sequence of tian gui while treating the liver and kidney simultaneously through time-sharing treatment should be effective. The use of Xiongcan Yishen Formula has shown promising therapeutic result, offering new insights and references for treating late onset hypogonadism in male using TCM.
Full text:2024121310400721281Discussion and treatment of late onset hypogonadism in male based ontian gui out of time sequence.pdf