Analysis of Patients with Hemoptysis in a Tertiary Referral Hospital.
10.4046/trd.2012.73.2.107
- Author:
Bo Ram LEE
1
;
Jin Yeong YU
;
Hee Jung BAN
;
In Jae OH
;
Kyu Sik KIM
;
Yong Soo KWON
;
Yu Il KIM
;
Young Chul KIM
;
Sung Chul LIM
Author Information
1. Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea. lscmd@jnu.ac.kr
- Publication Type:Original Article
- Keywords:
Hemoptysis;
Etiology;
Diagnosis;
Therapeutics;
Treatment Outcome
- MeSH:
Bronchial Arteries;
Bronchiectasis;
Diagnostic Tests, Routine;
Fungi;
Hemoptysis;
Hemorrhage;
Hospital Mortality;
Humans;
Lung Neoplasms;
Medical Records;
Prognosis;
Recurrence;
Retrospective Studies;
Tertiary Care Centers;
Treatment Outcome;
Tuberculosis, Pulmonary
- From:Tuberculosis and Respiratory Diseases
2012;73(2):107-114
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: This study attempted to investigate the main causes of hemoptysis, the type of examinations used for diagnosis, the treatment modalities and outcomes. METHODS: A retrospective study was conducted on the medical records of 221 patients admitted to the Chonnam National University Hospital, between January 2005 and February 2010, with hemoptysis. RESULTS: Bronchiectasis (32.6%), active pulmonary tuberculosis (18.5%), fungus ball (10.8%), and lung cancer (5.9%) accounted for most causes of hemoptysis. Computed tomography scan was the most sensitive diagnostic test when employed alone, with positive yield of 93.2%. There were 161 cases of conservative treatment (72.9%), 42 cases of bronchial artery embolization (BAE) (19.0%), and 18 cases of surgery (8.1%). Regarding the amount of hemoptysis, 70 cases, out of 221 cases, were mild (31.5%), 36 cases moderate (16.2%), and 115 cases massive hemoptysis (52.0%). Most of the patients were treated conservatively, but if there was more bleeding present, BAE or surgery was more commonly performed than the conservative treatment (p< or =0.0001). In the multivariate model, severe hemoptysis and lung cancer were independently associated with short-term recurrence. BAE was independently associated with long-term recurrence, and lung cancer was associated with in-hospital mortality. The overall in-hospital mortality rate was 11.3%. CONCLUSION: Hemoptysis is a common symptom with a good prognosis in most cases. However, patients exhibiting massive bleeding or those with malignancy had a poorer prognosis. In-hospital mortality was strongly related to the cause, especially in lung cancer.
