Unified consensus and evolution of the definition of acute-on-chronic liver failure:Seeking common ground while reserving differences
- VernacularTitle:求同存异,兼容并济——从国内外慢加急性肝衰竭定义的演变历程统一共识
- Author:
Manman XU
1
;
Yu CHEN
Author Information
- Keywords: Acute-on-Chronic Liver Failure; Definition; Evolution
- From: Journal of Clinical Hepatology 2024;40(11):2173-2176
- CountryChina
- Language:Chinese
- Abstract: The concept of acute-on-chronic liver failure(ACLF)has been introduced for nearly 30 years,and with extensive research on its pathogenesis,diagnostic criteria,and treatment strategies,related consensus statements and guidelines have been constantly updated in China and globally;however,there is still a lack of a unified definition of ACLF,and such differences in definition may inevitably hinder the application and implementation of various treatment methods,prognostic scoring systems,and clinical recommendations.In recent years,hepatology experts have continuously proposed methods to unify the definition of ACLF,seeking common ground while reserving differences and drawing on the strengths of various definitions,in order to achieve a more unified definition of ACLF.