The underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry

VernacularTitle:浅析抗病毒药物化学的底层逻辑、创新思维与研究范式
Author: Shuo WANG ¹ ; Bao-hu LI ^{1
,

2} ; Shu-jing XU ¹ ; Yang ZHOU ¹ ; Jin-fei YANG ³ ; Xin-yong LIU ¹ ; Peng ZHAN ¹
Author Information

1. Department of Medicinal Chemistry, School of Pharmaceutical Sciences, Shandong University, Jinan 250012, China
2. School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266001, China
3. School of Health and Life Sciences, University of Health and Rehabilitation Sciences, Qingdao 266001, China
Publication Type:Research Article
Keywords: medicinal chemistry; viral infection; rug design; research paradigm; small molecule drug
From: Acta Pharmaceutica Sinica 2024;59(7):1916-1931
CountryChina
Language:Chinese
Abstract: Antiviral drug research and development is an important research direction in the current and future biomedical field. The research and development of antiviral drugs not only requires the application of new strategies and new technologies, but also requires the complementary advantages and close cooperation of project teams. Based on the latest progress in this field and the author's drug research practice, this paper summarizes the underlying logic, innovative thinking and research paradigm of antiviral medicinal chemistry.