Research advances of pentacyclic triterpenoid natural products
10.16438/j.0513-4870.2023-1132
- VernacularTitle:五环三萜类天然产物研究进展
- Author:
Wen-xin DING
;
Bai-lin DU
;
Jiao LI
;
Chun-lin ZHUANG
- Publication Type:Research Article
- Keywords:
pentacyclic triterpene;
structural modification;
biological activity;
clinical study;
research progress
- From:
Acta Pharmaceutica Sinica
2024;59(5):1163-1175
- CountryChina
- Language:Chinese
-
Abstract:
Pentacyclic triterpenoids are a class of widespread natural compounds containing six isoprene structures with a wide range of pharmacological activities, including antibacterial, anti-inflammatory, antiviral, antitumor, immune regulation, etc. The structural modifications of pentacyclic triterpenoid natural products and the drug development have always been a hot research topic. This article reviews the recent progresses in the structural modifications, pharmacological effects, and clinical studies of different kinds of pentacyclic triterpenoid natural products.
