Role of Gut Microbiota in Cardiovascular Diseases and its Mechanism
10.13471/j.cnki.j.sun.yat-sen.univ(med.sci).20241021.005
- VernacularTitle:肠道微生物在心血管疾病中的作用及机制
- Author:
Yanyan SHU
1
;
Xuhong LIN
Author Information
1. 河南大学医学院,河南开封 475000
- Keywords:
gut microbiota;
metabolit intestinal flora;
cardiovascular diseases;
intestinal permeability;
role and mechanism;
treatment
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(6):994-1005
- CountryChina
- Language:Chinese
-
Abstract:
Cardiovascular diseases are now the leading cause of serious harms to human health,have drawn widespread attention both domestically and internationally. But the current research on mechanism of cardiovascular diseases is not keeping up with the current status of their treatment. The microbiota in the gut,the largest microecological system in the human body and its interaction with the human host have been implicated in a variety of diseases. The relationship between gut microbiota and cardiovascular diseases has been increasingly understood in recent years. The changes of gut microbiota and its metabolites are the major contributing factor for the occurrence and development of cardiovascular diseases,therefore,correction of gut microbiota dysbiosis may provide a novel therapeutic alternative for cardiovascular diseases. This article reviews the role of gut microbiota and its metabolites in cardiovascular diseases,aiming to provide reference for future related studies.
