Drug prophylaxis evidence-based regimens for venous thromboembolism after joint replacement
- VernacularTitle:关节置换术后静脉血栓栓塞症的药物预防循证方案
- Author:
Xiaowei FENG
1
,
2
;
Na GUO
2
;
Baozhen WANG
2
;
Jie CHENG
2
;
Yuchen TANG
2
;
Jun QI
2
;
Zhiqiang DONG
2
Author Information
1. School of Pharmacy，Baotou Medical College，Inner Mongolia University of Science & Technology，Inner Mongolian Baotou 014040，China
2. Dept. of Pharmaceutical Clinical Research，the First Affiliated Hospital of Baotou Medical College，Inner Mongolia University of Science & Technology，Inner Mongolian Baotou 014040，China
- Publication Type:Journal Article
- Keywords:
venous thromboembolism;
artificial joint
- From:
China Pharmacy
2024;35(22):2799-2807
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To sort out drug prophylaxis regimens for venous thromboembolism （VTE） in adult patients after artificial joint replacement， and provide a basis for clinic. METHODS Databases and related official websites were searched according to the “6S” model， including the National Institute for Health and Clinical Excellence （NICE）， the Scottish Intercollegiate Guidelines Network （SIGN）， the Guidelines International Network （GIN）， the National Guidelines Clearinghouse （NGC）， PubMed， Embase， CNKI， Wanfang database and SinoMed， to search for guidelines， expert consensuses， systematic evaluations， randomized controlled trials， and cohort studies about preventing VTE in adult patients after artificial joint replacement from the inception until December 2023. Literature that met the inclusion criteria were selected， and the quality evaluation of the literature was completed by 2 researchers independently； the evidence rating was performed by using the Joanna Briggs Institute （JBI） evidence pre-classification and evidence rank system （2014 edition）. RESULTS A total of 36 articles were included in the study， which were categorized into 9 areas of risk assessment， post-assessment prophylaxis， medication selection， medication method， duration of medication prophylaxis， medication prophylaxis observation points， contraindications to drug prophylaxis， response to bleeding， and health education， which were summarized to form 37 pieces of evidence on the pharmacological prophylaxis for postoperative VTE in patients who underwent artificial joint replacement. CONCLUSIONS The evidence of drug prophylaxis for postoperative VTE in patients who underwent artificial joint replacement summarized in this study is comprehensive， with certain scientific reference and practicality， which can provide clinical pharmacists with a scientific evidence-based basis for perioperative VTE prophylaxis management.
