Evaluation value of contrast-enhanced ultrasound and contrast-enhanced spiral CT in the TACE treatment of primary hepatocellular carcinoma
10.13491/j.issn.1004-714X.2024.05.019
- VernacularTitle:CEUS和增强螺旋CT对原发性肝细胞癌TACE治疗效果的评估价值
- Author:
Zongbao HAN
1
;
Xi LI
1
;
Ziyi LIANG
1
;
Rengui WANG
1
Author Information
1. Beijing Shijitan Hospital Affiliated to Capital Medical University, Beijing 100038 China.
- Publication Type:OriginalArticles
- Keywords:
Primary hepatocellular carcinoma;
Contrast-enhanced ultrasound;
Contrast-enhanced spiral CT;
Efficacy;
Evaluation
- From:
Chinese Journal of Radiological Health
2024;33(5):600-606
- CountryChina
- Language:Chinese
-
Abstract:
Objective Analyze and compare the therapeutic value of contrast-enhanced ultrasound (CEUS) and enhanced spiral CT in patients with primary hepatocellular carcinoma (PHC) undergoing transcatheter arterial chemoembolization (TACE). Methods A retrospective analysis was conducted on 108 PHC patients (122 lesions) treated at Beijing Shijitan Hospital affiliated with Capital Medical University from July 2021 to June 2023. All patients were treated with TACE. After treatment, CEUS and contrast-enhanced spiral CT examinations were performed to evaluate the inactivation status of tumor lesions, with pathological results as the gold standard. The receiver operating characteristic curve and decision tree model were used to comprehensively evaluate the diagnostic value of CEUS, contrast-enhanced spiral CT, and their combination in PHC. Results The pathological results showed that 79 lesions remained active (positive) and 43 lesions were completely inactivated (negative). The areas under the receiver operating characteristic curve for evaluating PHC treatment efficacy by CEUS, contrast-enhanced spiral CT, and their combination were 0.975, 0.918, and 0.994, respectively. The sensitivity, positive predictive value, and actual application accuracy of CEUS and the combined method were higher than those of contrast-enhanced spiral CT (P < 0.05). A decision tree diagnostic model for PHC treatment efficacy was constructed using CEUS, contrast-enhanced spiral CT, and their combination as independent variables and PHC treatment efficacy as the dependent variable. The misjudgment rates were 3.3%, 10.7%, and 0.8%, respectively, and the prediction accuracy was 96.7%, 89.3%, and 99.2%, respectively. Conclusions CEUS and the combination of CEUS and contrast-enhanced spiral CT have high evaluation value for PHC treatment efficiency.
