Exploring the Application of Regulating Tumour Immunity and Anti-tumour Metastasis by Invigorating Blood Method Based on the Theory of Qi Channels
10.13288/j.11-2166/r.2024.20.017
- VernacularTitle:基于气络学说探讨活血法在调控肿瘤免疫、抗肿瘤转移中的应用
- Author:
Jing WANG
1
;
Peitong ZHANG
2
;
Rui MIAO
1
;
Ruoqi ZHANG
1
;
Jie HE
3
Author Information
1. Graduate School,Beijing University of Chinese Medicine,Beijing,100029
2. Guang'anmen Hospital,China Academy of Chinese Medical Sciences
3. Women and Children's Hospital,School of Medicine,Xiamen University
- Publication Type:Journal Article
- Keywords:
tumour immunity;
immunosuppressive;
qi channels;
invigorate blood
- From:
Journal of Traditional Chinese Medicine
2024;65(20):2163-2165
- CountryChina
- Language:Chinese
-
Abstract:
According to the theory of qi channels, we explored the relationship of the method of invigorating blood and regulating tumour immunity, to provide ideas and methods for traditional Chinese medicine for regulating tumour immunity and anti-tumour metastasis. It is believed that qi channels are closely related to tumour immunity, and qi channels are equivalent to immune networks such as immune cells and immune factors with anti-tumour immunity in the tumour immune micro-environment. Combined with the physiological function and pathological characteristics of qi channels, it is proposed that the pathogenesis of qi channels-related disease due to qi channels failing to govern, blood stasis obstructing, and qi channels deficiency and stagnation as the basis for the occurrence of tumour immunosuppression and metastasis, and that qi channels constraint and stagnation as the condition for the occurrence of tumour immunosuppression and metastasis. In view of the pathomechanism of tumour immune escape caused by qi channels failing to govern, it is proposed that the therapeutic principle of regulating qi and channels to regulate tumour immunity by invigorating blood circulation method could be "performing functions when there is free flow, reaching the expectation when balanced", and the key of treatment is to regulate qi and channels, unblock the collaterals to dispel stasis.