Discussion on Treatment of Gastric "Inflammation-cancer" Transformation based on the "Five-view Differentiation and Treatment" System
10.13288/j.11-2166/r.2024.19.007
- VernacularTitle:基于“五观辨治”体系论治胃“炎-癌”转化
- Author:
Yuansha GE
1
;
Bowen XU
1
;
Jie LI
1
Author Information
1. Guang'anmen Hospital，China Academy of Chinese Medical Sciences，Beijing，100053
- Publication Type:Journal Article
- Keywords:
precancerous lesions of gastric cancer;
inflammation-cancer transformation;
Correa evolution
- From:
Journal of Traditional Chinese Medicine
2024;65(19):1988-1993
- CountryChina
- Language:Chinese
-
Abstract:
Standardized gastroscopy screening makes the diagnosis of precancerous lesions of gastric cancer （PLGC） clearer. Correa evolution is the key to gastritis-cancer transformation， suggesting that PLGC is the core of the body's transformation from normal to cancer. Based on the "five-view differentiation and treatment" system for malignant tumors， we explored the establishment of a new system for preventing and treating malignant transformation of benign and inflammatory lesions from five dimensions， including pre-disease view， time-space view， core view， symptoms view and precision view. （a） pre-disease view： early intervention to intercept inflammation-cancer transformation； （b） time-space view： following the time-space framework as the disease progresses； （c） core view： focusing on the core pathogenesis of inflammation-cancer transformation. In terms of different stages， qi deficiency and stagnation are mainly manifested in the early stage， which can be treated by invigorating qi and resolving constraint； in the middle stage， yin turbidity is blocked internally， and it can be treated by warming yang and removing turbidity； in the cancerous stage， cancer toxin are blocked， for which the anti-cancer， toxins-resolving and stasis-dissolving method is suggested. In terms of the location of the disease， it is suggested to relieve disease in the upper body by rectifying qi and dissolving phlegm with emetic therapy （vomit induction）； for the disease in the middle， it it suggested to nourish yin and clear heat by elimination method； pathogen in the lower requires dredging method by moving qi and dissipating cold； （d） symptoms view： using herbal pairs to deal with the main symptoms； （e） precision view： enriching targets to prevent and control cancer directionally.
