Treatment of Amyotrophic Lateral Sclerosis by the Method of Lifting the Sunken from "Deficiency,Toxin, Wind-Heat"
10.13288/j.11-2166/r.2024.23.015
- VernacularTitle:运用举陷法从“虚、毒、风热”论治肌萎缩侧索硬化症
- Author:
Huan YU
1
;
Yongkang SUN
1
;
Yanbo SONG
1
;
Xinzhi WANG
1
Author Information
1. The First Affiliated Hospital of Henan University of Chinese Medicine,Zhengzhou,450099
- Publication Type:Journal Article
- Keywords:
amyotrophic lateral sclerosis;
general qi deficiency sinking;
method of lifting the sunken
- From:
Journal of Traditional Chinese Medicine
2024;65(23):2476-2481
- CountryChina
- Language:Chinese
-
Abstract:
It is regarded that the general qi is the combination of spleen-kidney qi and heart-lung yang qi in the chest, which is filled between the muscles and is able to maintain the normal shape of the muscles. Accordingly, it is proposed that the core pathogenesis of amyotrophic lateral sclerosis (ALS) is the deficiency sinking of general qi, with "deficiency" as the root, and "toxin" and "wind-heat" as the key factors for the rapid progression of the disease. The development process of ALS was classified into the initial onset stage, the increasingly progressive stage, and the rapid exacerbation stage, and differentiated and treated by deficiency, toxin, and wind-heat. Based on clinical experience, the wind medicinals were preferred. We formed self-prescribed Juxian Decoction (举陷汤) and modified from the perspective of "deficiency, toxicity, wind-heat" based on the wind medicinals of Huangqi (Radix Astragali), Shengma (Actaea cimicifuga L.), Chaihu (Bupleurum spp.) and so on. For the initial onset stage, Yiqi Shengji Juxian Decoction (益气生肌举陷汤), Wenyang Liyan Juxian Decoction (温阳利咽举陷汤) could be used; for the increasingly progressive stage, Jiedu Juxian Decoction (解毒举陷汤) could be used; for the rapid exacerbation stage, Yinqiao Shufen Juxian Decoction (银翘疏风举陷汤), Yangxue Xifeng Juxian Decoction (养血熄风举陷汤) could be used.