Biological principles of "food and medicine homologous"
10.16438/j.0513-4870.2024-0284
- VernacularTitle:“食药同源”的生物学原理
- Author:
Jin-wen DING
1
;
Xiang-yin CHI
1
;
Yu ZHANG
1
;
Lu-lu WANG
2
;
Jian-dong JIANG
1
,
3
;
Yuan LIN
1
Author Information
1. State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
2. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
3. Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China
- Publication Type:Research Article
- Keywords:
food and medicine homologous;
preventive treatment of disease;
intestinal flora;
chemical basis;
pharmacological activity;
Biao Ben Jian Zhi
- From:
Acta Pharmaceutica Sinica
2024;59(6):1509-1518
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid society development and broad recognition of "Healthy China", the demands for good life and health are increasing. Accordingly, the concept of "food and medicine homologous" have been attractive. The concept of "food and medicine homologous" has a long history in China, and is an essence of various ideas in traditional Chinese medicine, such as diet therapy, medicated diet, regimen and preventive treatment of disease, representing an important field in health science. Many studies have found that the active ingredients of "food and medicine homologous" substances are multiple types, multiple mechanisms and multiple targets, exerting their biological effects after oral administration and chemical or metabolic transformation. In this review, the chemical basis and biological principles of various "food and medicine homologous" substances were summarized as compounds, biological macromolecules and intestinal flora. By focusing on the intestinal flora, we discussed the detailed biological principles of several classic "food and medicine homologous" substances. The scientific significance of "food and medicine homologous" concept were also discussed. This review explores the concept of "food and medicine homologous" from the perspective of modern medicine, in order to provide insights for future drug development and human health.
