An unusual case of adrenocortical carcinoma with multiple facets

Author: Jie En Tan ¹ ; Florence Hui Sieng Tan ¹ ; Yueh Chien Kuan ¹ ; Pei Lin Chan ¹ ; Yusri Yusuf ²
Author Information

1. Endocrine Unit, Department of Medicine, Sarawak General Hospital, Ministry of Health, Malaysia
2. Pathology Department, Sarawak General Hospital, Ministry of Health, Malaysia
Publication Type:Case Reports
Keywords: urine fractionated metanephrines
MeSH: Adrenocortical Carcinoma; Pheochromocytoma
From: Journal of the ASEAN Federation of Endocrine Societies 2024;39(2):92-96
CountryPhilippines
Language:English
Abstract: Adrenocortical carcinoma (ACC) is a rare malignant tumour originating from the adrenal cortex. Half of the cases are functional, with ACTH independent autonomous cortisol production being the most common. It is rare for ACC to present with markedly elevated metanephrine levels which is a typical characteristic of pheochromocytoma. We report a case of a large functioning adrenal tumour with overlapping biochemistry features of ACC and pheochromocytoma. Biopsy confirmed the histopathological diagnosis of metastatic ACC.
Full text:202411291503367684208_5pp.pdf