Pathogenesis of Refractory Rheumatoid Arthritis with Healthy Qi Deficiency and Toxins Accumulation
10.13288/j.11-2166/r.2024.22.014
- VernacularTitle:难治性类风湿关节炎正虚毒蕴病机论
- Author:
Wei LIU
1
;
Yuxiu KA
1
;
Shujuan CHEN
1
Author Information
1. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine，Tianjin，300193
- Publication Type:Journal Article
- Keywords:
refractory rheumatoid arthritis;
pathogenesis;
healthy qi deficiency and toxins accumulation;
reinforce healthy qi and resolve toxins;
latent toxins
- From:
Journal of Traditional Chinese Medicine
2024;65(22):2368-2372
- CountryChina
- Language:Chinese
-
Abstract:
Refractory rheumatoid arthritis belongs to the category of "stubborn bi （痹）" and "lame bi" in traditional Chinese medicine. It is believed that pathogenic toxin is an important pathogenic factor of refractory rheumatoid arthritis， and "healthy qi deficiency and toxins accumulation" is its core pathogenesis. Pathogenic toxin can be divided into latent and internal toxin， among which latent toxin includes congenital latent toxin and acquired exogenous and drug-induced latent toxin； and internal toxin is directly produced by the dysfunction of the body's zang-fu （脏腑） organs， or is transformed from dampness， turbidity， phlegm and stasis. Pathogenic toxin can flow into the meridians and collaterals， quickly corrode the bones and joints， harm the five zang organs， secretly consume the body's healthy qi， and accumulate and entrench. Based on this， the treatment principle of "reinforcing healthy qi and resolving toxins" has been established， emphasizing that the key is to strengthen the origin of the body's healthy qi and to attack the pathogenic toxin from its weakness. In clinical practice， it is suggested to trace the root cause， and treat the disease based on the cause. Besides reinforcing the body's healthy qi， the methods such as clearing heat to resolve toxins， draining dampness to resolve toxins， dispelling wind to remove toxins， dispersing cold to resolve toxins， dissolving phlegm to resolve toxins， and dispersing stasis to resolve toxins can be supplemented， so as to reinforce the healthy qi and dispel pathogens simultaneously and thereby improving the clinical efficacy.
