Scientific Connotations of "Reinforcing Earth for Generating Metal" in the Treatment of Lung Cancer from the Perspective of the Microecology of Intestinal Microbiota
10.13288/j.11-2166/r.2024.22.002
- VernacularTitle:从肠道菌群微生态角度探讨“培土生金”法辨治肺癌的科学内涵
- Author:
Yiyun HE
1
;
Yabin GONG
1
;
Lijing JIAO
1
;
Ling XU
1
Author Information
1. Department One of Oncology,Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine, Shanghai,200437
- Publication Type:Journal Article
- Keywords:
lung cancer;
reinforcing earth for generating metal;
intestinal microbiota;
intestinal microecology
- From:
Journal of Traditional Chinese Medicine
2024;65(22):2287-2293
- CountryChina
- Language:Chinese
-
Abstract:
"Reinforcing earth for generating metal" is based on the treatment principle of the five-element theory of traditional Chinese medicine (TCM), which states that "reinforcing mother viscera for treating deficiency of child viscera". Based on the principle of inter-generating relationship in the five elements that earth generates metal, by strengthening the functions of the internal organs belonging to "earth" (spleen and stomach) to indirectly nourish the internal organs belonging to "metal" (lungs and large intestine). Using reinforcing earth for generating metal in the treatment of lung cancer, according to the principle of "reinforcing mother viscera for treating deficiency of child viscera", by strengthening the function of "earth" viscera, the treatment effect of "metal" viscera can be achieved. The metabolic disorder, inflammatory response, and immune regulation caused by the changes in the composition and structure of intestinal microbiota are involved in the occurrence and development of lung cancer, which is consistent with the theory of “the external and internal relationship between the lung and the large intestine” in TCM. From the perspective of intestinal microbiota microecology, the paper discusses the pathogenesis of "earth disease leads to metal disorders" that the gut microbiota dysbiosis causes lung cancer and the treatment method of "reinforcing earth for generating metal" by regulating the microecological balance of gut microbiota in lung cancer, suggesting the great significance of "reinforcing earth for generating metal" therapy aiming at microecological balance of gut microbiota in the treatment of lung cancer, in order to provide a different perspective for the treatment of lung cancer with TCM.