Changes of corneal densitometry in patients with keratoconus after corneal collagen cross-linking
10.3980/j.issn.1672-5123.2024.12.17
- VernacularTitle:圆锥角膜患者角膜交联术后角膜光密度的变化
- Author:
Shuai LI
1
;
Yang GAO
1
;
Limei MA
1
;
Rui LI
1
;
Yixuan QIN
1
;
Caihong SUN
1
;
Yu HAN
1
;
Jinjin ZHANG
1
;
Wenjuan ZHUANG
1
Author Information
1. North Minzu University, Yinchuan 750030, Ningxia Hui Autonomous Region, China
- Publication Type:Journal Article
- Keywords:
keratoconus;
corneal cross-linking;
corneal densitometry
- From:
International Eye Science
2024;24(12):1954-1958
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To observe the changes of corneal densitometry(CD)in patients with keratoconus after corneal cross-linking(CXL).METHODS: Retrospective study. A total of 32 patients(43 eyes)with keratoconus in Ningxia Eye Hospital from April 2020 to April 2022 were selected. Pentacam analysis system divided the cornea into three layers: anterior 120 μm, middle layer and posterior 60 μm, and divides it into five regions with diameters of 0-2, 2-6, 6-10, 10-12 mm and full diameter according to the diameter, and measures the CD in different ranges. The changes of CD were compared before operation and at 1, 3 and 6 mo after operation.RESULTS: There were differences in uncorrected visual acuity, best corrected visual acuity and intraocular pressure before and 6 mo after operation(all P<0.05), and there was no difference in corneal endothelial cells(P=0.477). CD reached its peak at 1 mo after operation, and decreased at 3 mo and 6 mo after operation, but it was still higher than that before operation. There is a significant positive correlation between CD and Kmax in the anterior layer and the whole layer(r=0.164, P=0.016; r=0.152, P=0.023).CONCLUSION: The values of CD peaked at 1 mo after CXL, then it gradually decreased, tending to become stable at 6 mo postoperatively.
