Advances in prophylaxis and treatment of retinal detachment related to Stickler syndrome
10.3980/j.issn.1672-5123.2024.12.14
- VernacularTitle:Stickler综合征相关视网膜脱离的防治研究进展
- Author:
Xu GAO
1
;
Yuan YANG
1
;
Ping FEI
1
;
Jie PENG
1
;
Tingyi LIANG
1
;
Mengxiao WU
1
;
Peiquan ZHAO
1
Author Information
1. Department of Ophthalmology, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China
- Publication Type:Journal Article
- Keywords:
Stickler syndrome;
retinal detachment;
rhegmatogenous retinal detachment;
retinal reattachment;
prophylaxis;
surgery
- From:
International Eye Science
2024;24(12):1939-1944
- CountryChina
- Language:Chinese
-
Abstract:
Stickler syndrome is a hereditary connective tissue disorder, characterized in ocular manifestations by high myopia and vitreous abnormalities. The progression of the disease can lead to giant retinal tear and rhegmatogenous retinal detachment, making it the most common cause of inherited pediatric retinal detachment. Surgical intervention is the primary treatment for retinal detachment associated with Stickler syndrome. However, there are currently no evidence-based management strategies. Patients typically require multiple surgeries, with low reattachment rates and high recurrence rates, emphasizing the importance of prophylactic treatment. Current prophylactic measures include scleral bucking, laser photocoagulation and retinal cryotherapy, but their absolute benefits remain insufficiently supported. This review summarizes recent advances in the prophylaxis and treatment of retinal detachment in Stickler syndrome, aiming to provide new insights and essential references for the prevention and treatment for such conditions.
