Early outcomes of domestic left ventricular assist device implantation with or without concomitant mitral valvuloplasty
- VernacularTitle:国产左心室辅助装置植入是否同期行二尖瓣成形术的早期临床结果
- Author:
Zhihua WANG
1
;
Zeyuan ZHAO
1
;
Junlong HU
1
;
Junjie SUN
1
;
Kun LIU
2
;
Xiaoxia DUAN
1
;
Sheng WANG
1
;
Zhaoyun CHENG
1
Author Information
1. Department of Cardiac Surgery, Zhengzhou University Affiliated Fuwai Central China Cardiovascular Hospital, Zhengzhou, 451464, P. R. China
2. Department of Cardiac Surgery, Cardiovascular Medical Center, the University of Hong Kong-Shenzhen Hospital, Shenzhen, 518053, Guangdong, P. R. China
- Publication Type:Journal Article
- Keywords:
Heart failure;
left ventricular assist device;
mitral regurgitation;
mitral valvuloplasty;
early outcomes
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(11):1599-1605
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the early outcomes of domestic third-generation magnetically levitated left ventricular assist device (LVAD) with or without concomitant mitral valvuloplasty (MVP). Methods The clinical data of 17 end-stage heart failure patients who underwent LVAD implantation combined with preoperative moderate to severe mitral regurgitation in Fuwai Central China Cardiovascular Hospital from May 2018 to March 2023 were retrospectively analyzed. The patients were divided into a LVAD group and a LVAD+MVP group based on whether MVP was performed simultaneously, and early outcomes were compared between the two groups. Results There were 4 patients in the LVAD group, all males, aged (43.5±5.9) years, and 13 patients in the LVAD+MVP group, including 10 males and 3 females, aged (46.8±16.7) years. All the patients were successful in concomitant MVP without mitral reguragitation occurrence. Compared with the LVAD group, the LVAD+MVP group had a lower pulmonary artery systolic pressure and pulmonary artery mean pressure 72 h after operation, but the difference was not statistically different (P>0.05). Pulmonary artery systolic pressure was significantly lower 1 week after operation, as well as pulmonary artery systolic blood pressure and pulmonary artery mean pressure at 1 month after operation (P<0.01). There was no statistically significant difference in blood loss, operation time, cardiopulmonary bypass time, aortic cross-clamping time, mechanical ventilation time, or ICU stay time between the two groups (P>0.05). The differences in 1-month postoperative mortality, acute kidney injury, reoperation, gastrointestinal bleeding, and thrombosis and other complications between the two groups were not statistically significant (P>0.05). Conclusion Concomitant MVP with implantation of domestic third-generation magnetically levitated LVAD is safe and feasible, and concomitant MVP may improve postoperative hemodynamics without significantly increasing perioperative mortality and complication rates.
