Early efficacy of "one-stop" transapical transcatheter aortic valve replacement combined with mitral valve edge-to-edge repair in the treatment of multivalvular disease
- VernacularTitle:“一站式”经心尖经导管主动脉瓣置换术联合二尖瓣缘对缘修复术治疗多瓣膜病变的早期疗效分析
- Author:
Wenhui GONG
1
;
Xiaoyong WEI
1
;
Xiaotian GAO
1
;
Jinguo XU
1
;
Guangdong WENG
1
;
Chengxin ZHANG
1
Author Information
1. Department of Cardiovascular Surgery, The First Affiliated Hospital of Anhui Medical University, Hefei, 230088, P. R. China
- Publication Type:Journal Article
- Keywords:
Critical multivalvular disease;
"one-stop";
transapical transcatheter aortic valve replacement;
transapical transcatheter mitral valve edge-to-edge repair
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(10):1467-1474
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the feasibility and early efficacy of transapical transcatheter aortic valve replacement (TAVR) combined with transcatheter mitral valve edge-to-edge repair (TEER) in patients with high-risk aortic valve lesions combined with severe mitral regurgitation. Methods The clinical data of patients who underwent "one-stop" transapical TAVR+TEER in our hospital from August 2022 to October 2023 were retrospectively analyzed. Results Five patients were collected, including 3 males and 2 females with a mean age of 66.6±1.8 years. Four patients had aortic valve insufficiency combined with mitral regurgitation and one had aortic valve stenosis and insufficiency combined with mitral regurgitation. All patients successfully completed transapical TAVR+TEER, and the immediate postoperative echocardiographic results revealed that none of them had more than mild perivalvular leakage and mitral regurgitation, and the prosthetic valves were in good position and function. At 1 week postoperatively, echocardiographic results showed 5 patients with no displacement of the prosthetic valve, detachment of the mitral clip, or damage to the leaflets. At 1 month postoperatively, cardiac function was improved to varying degrees in 4 patients, and 1 patient died of multiorgan failure. At 2 months postoperatively, 1 patient died of cerebrovascular accident, and at 3 months postoperatively the echocardiographic results of the remaining 3 patients revealed that there was no more than mild perivalvular leakage or mitral regurgitation, and the patients' postoperative cardiac function and daily life ability were significantly improved. Conclusion In high-risk aortic valve lesions combined with severe mitral regurgitation, "one-stop" transapical TAVR+TEER is feasible with favorable early efficacy and safety.
