Clinical risk factors for early adverse cardiovascular events after surgical correction of supravalvar aortic stenosis: A retrospective cohort study
- VernacularTitle:主动脉瓣上狭窄术后早期心血管不良事件临床危险因素的回顾性队列研究
- Author:
Simeng ZHANG
1
,
2
;
Caiyi WEI
3
;
Lizhi lǚ
4
;
Bo PENG
5
,
6
;
Jianming XIA
7
;
Qiang WANG
4
;
Jun YAN
5
,
6
;
Yi SHI
1
,
2
Author Information
1. Department of Cardiac Surgery, Peking University People&rsquo
2. s Hospital, Beijing, 100044, P. R. China
3. School of Basic Medical Sciences, Peking University, Beijing, 100191, P. R. China
4. Center for Pediatric Cardiac Surgery, Beijing Anzhen Hospital, Capital Medical University, Beijing, 100029, P. R. China
5. Department of Cardiac Surgery, National Center for Cardiovascular Diseases and Fuwai Hospital, Chinese Academy of Medical Sciences &
6. Peking Union Medical College, Beijing, 100037, P. R. China
7. Department of Cardiac Surgery, Fuwai Yunnan Cardiovascular Hospital, Kunming, 650102, P. R. China
- Publication Type:Journal Article
- Keywords:
Congenital heart disease;
supravalvar aortic stenosis;
surgical treatment;
adverse cardiovascular events;
risk factors
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(10):1448-1454
- CountryChina
- Language:Chinese
-
Abstract:
Objective To identify clinical risk factors for early major adverse cardiovascular events (MACEs) following surgical correction of supravalvar aortic stenosis (SVAS). Methods Patients who underwent SVAS surgical correction between 2002 and 2019 in Beijing and Yunnan Fuwai Cardiovascular Hospitals were included. The patients were divided into a MACEs group and a non-MACEs group based on whether MACEs concurring during postoperative hospitalization or within 30 days following surgical correction for SVAS. Their preoperative, intraoperative, and postoperative clinical data were collected for multivariate logistic regression. Results This study included 302 patients. There were 199 males and 103 females, with a median age of 63.0 (29.2, 131.2) months. The incidence of early postoperative MACEs was 7.0% (21/302). The multivariate logistic regression model identified independent risk factors for early postoperative MACEs, including ICU duration (OR=1.01, 95%CI 1.00-1.01, P=0.032), intraoperative cardiopulmonary bypass (CPB) time (OR=1.02, 95%CI 1.01-1.04, P=0.014), aortic annulus diameter (OR=0.65, 95%CI 0.43-0.97, P=0.035), aortic sinus inner diameter (OR=0.75, 95%CI 0.57-0.98, P=0.037), and diameter of the stenosis (OR=0.56, 95%CI 0.35-0.90, P=0.016). Conclusion The independent risk factors for early postoperative MACEs include ICU duration, intraoperative CPB time, aortic annulus diameter, aortic sinus inner diameter, and diameter of the stenosis. Early identification of high-risk populations for MACEs is beneficial for the development of clinical treatment strategies.
