Domestic self-expanding interventional pulmonary valve stent in transthoracic implantation for pulmonary valve regurgitation: A prospective cohort study
- VernacularTitle:国产自膨式介入肺动脉瓣支架经胸植入术治疗肺动脉瓣反流的前瞻性队列研究
- Author:
Ziqin ZHOU
1
;
Taoran HUANG
2
;
Naijimuding ABUDUREXITI
1
;
Yong ZHANG
1
;
Haiyun YUAN
1
;
Nianjin XIE
3
;
Hongwen FEI
2
;
Hui LIU
4
,
5
;
Jian ZHUANG
1
;
Jimei CHEN
1
;
Shusheng WEN
1
Author Information
1. 1.Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China 2.Department of Cardiovascular Surgery, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China
2. 1.Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China 3.Department of Cardiology, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China
3. 1. Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China 4. Department of Adult Echocardiography, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China
4. 1.Guangdong Cardiovascular Institute, Guangdong Provincial People&rsquo
5. s Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, 510080, P. R. China 5.Department of Radiology, Guangdong Cardiovascular Institute, Guangdong Provincial People s Hospital, Guangdong Academy of Medical Sciences, Guangzhou, 510080, P. R. China
- Publication Type:Journal Article
- Keywords:
Self-expanding pulmonary valve stent;
pulmonary valve regurgitation;
right ventricular outflow tract;
right heart function
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(09):1305-1312
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze and summarize the early and medium-term outcomes of self-expanding interventional pulmonary valve stent (SalusTM) for right ventricular outflow tract dysfunction with severe pulmonary valve regurgitation. Methods We established strict enrollment and follow-up criteria. Patients who received interventional pulmonary valve in transthoracic implantation in Guangdong Provincial People’s Hospital from September 2, 2021 to July 18, 2023 were prospectively included, and all clinical data of patients were collected and analyzed. Results A total of 38 patients with severe pulmonary regurgitation were included, with 23 (60.5%) males and 15 (39.5%) females. The mean age was 24.08±8.12 years, and the mean weight was 57.66±13.54 kg. The preoperative mean right ventricular end-diastolic volume index (RVEDVI) and right ventricular end-systolic volume index (RVESVI) were 151.83±42.84 mL/m2 and 83.34±33.05 mL/m2, respectively. All patients successfully underwent transcatheter self-expandable pulmonary valve implantation, with 3 (7.9%) patients experiencing valve stent displacement during the procedure. Perioperative complications included 1 (2.6%) patient of postoperative inferior wall myocardial infarction and 1 (2.6%) patient of poor wound healing. The median follow-up time was 12.00 (6.00, 17.50) months. During the follow-up period, there were no deaths or reinterventions, and no patients had recurrent severe pulmonary regurgitation. Three (7.9%) patients experienced chest tightness and chest pain, and 1 (2.6%) patient developed frequent ventricular premature beats. Compared with preoperative values, the right atrial diameter, right ventricular diameter, and tricuspid annular plane systolic excursion were significantly reduced at 6 months and 1 year postoperatively, with improvement in the degree of pulmonary regurgitation (P<0.01). Compared with preoperative values, RVEDVI and RVESVI decreased to 109.51±17.13 mL/m2 and 55.88±15.66 mL/m2, respectively, at 1 year postoperatively (P<0.01). Conclusion Self-expanding interventional pulmonary valve in transthoracic implantation is safe and effective for severe pulmonary valve regurgitation and shows good clinical and hemodynamic results in one-year outcome.
