Association of hypertension onset age with diabetes
10.19485/j.cnki.issn2096-5087.2024.11.001
- Author:
GAO Hui
;
ZHU Xuting
;
ZHANG Lei
;
XIA Qinghua
;
WANG Yingquan
;
ZHANG Yanping
;
XU Jiangmin
;
SHI Yue
;
SHI Wuyue
;
JIANG Yu
;
WAN Jinbao
- Publication Type:Journal Article
- Keywords:
hypertension;
onset age;
prediabetes;
diabetes
- From:
Journal of Preventive Medicine
2024;36(11):921-925,930
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To examine the association of hypertension onset age with diabetes, so as to provide insights into reducing the the risk of cardiovascular events.
Methods:Permanent residents aged 35 to 75 years were selected through the program of early screening and comprehensive intervention for the high-risk cardiovascular disease population in Changning District and Baoshan District, Shanghai Municipality from 2016 to 2020. Demographic information, disease history, hypertension onset age, blood pressure and fasting blood glucose were collected through questionnaire surveys, physical examination and laboratory tests. The residents were divided into four groups based on the onset age of hypertension: <45, 45-<55, 55-<65 and ≥65 years old, and the residents with normal blood pressure were selected as control. The association of hypertension onset age with prediabetes and diabetes were identified using a multivariable logistic regression model.
Results:A total of 25 228 residents were recruited, including 8 753 males (34.70%) and 16 475 females (65.30%). The prevalence of hypertension was 43.80%. There were 1 779, 3 274, 3 781 and 2 217 cases with hypertension onset age of <45, 45-<55, 55-<65 and ≥65 years old, respectively, and 14 177 residents with normal blood pressure. The prevalence of prediabetes and diabetes were 24.01% and 11.29%, respectively. Multivariable logistic regression analysis showed that after adjusting for confounding factors such as gender, marital status and educational level, compared with the normal blood pressure group, the risk of prediabetes was higher in the hypertension onset age groups of <45 (OR=1.345, 95%CI: 1.164-1.553), 45-<55 (OR=1.365, 95%CI: 1.212-1.536) and 55-<65 years old (OR=1.376, 95%CI: 1.239-1.527), and the risk of diabetes was higher in the hypertension onset age groups of <45 (OR=2.302, 95%CI: 1.906-2.775), 45-<55 (OR=2.349, 95%CI: 2.016-2.734), 55-<65 (OR=1.909, 95%CI: 1.667-2.184) and ≥65 years old (OR=1.315, 95%CI: 1.131-1.526).
Conclusion:There are statistically significant associations between hypertension onset age with prediabetes and diabetes.
- Full text:2024111811261369521高血压发病年龄与糖尿病的关联研究.pdf
