Diagnosis and treatment of thrombocytopenia after liver transplantation
10.3969/j.issn.1674-7445.2024181
- VernacularTitle:肝移植术后血小板减少的诊断与治疗
- Author:
Tao CAI
1
;
Jinglin CAO
;
Jian DOU
;
Qiang ZENG
Author Information
1. 050051 石家庄,河北医科大学第三医院肝胆外科
- Keywords:
Thrombocytopenia;
Liver Transplantation;
Thrombopoietin;
A disintegrin and metalloproteinase with thrombospondin type 1 motifs 13;
Hypersplenism;
Marginal Donor;
Infection;
Immunosuppressive drug
- From:
Organ Transplantation
2024;15(6):964-969
- CountryChina
- Language:Chinese
-
Abstract:
Thrombocytopenia is one of the common complications after liver transplantation,with pathophysiological mechanisms including insufficient platelet production and increased platelet consumption,which severely affects the prognosis of liver transplant recipients.Various factors such as preoperative hepatitis virus infection,intraoperative ischemic injury,and postoperative use of immunosuppressive drugs may lead to thrombocytopenia after liver transplantation.Early detection and effective treatment of thrombocytopenia after liver transplantation are currently hot topics of research.Based on the existing literature,this article reviews the definition,pathophysiological mechanisms,risk factors,treatment,and prevention of thrombocytopenia,and discusses the occurrence and development of thrombocytopenia after liver transplantation and related diagnosis and treatment strategies,aiming to optimize the existing treatment opinions,reduce the risk of thrombocytopenia after transplantation and improve the prognosis of liver transplant recipients.
