Advances and prospects of conversion surgery for unresectable esophageal squamous cell carcinoma
- VernacularTitle:不可切除食管鳞癌转化手术的研究进展及前景
- Author:
Xingqiang RAN
1
;
Guidong SHI
1
;
Yu ZHOU
1
;
Hao YANG
1
;
Hao DING
1
;
Maoyong FU
1
Author Information
1. Department of Thoracic Surgery, Affiliated Hospital of North Sichuan Medical College, Nanchong, 637000, Sichuan, P. R. China
- Publication Type:Journal Article
- Keywords:
Esophageal squamous cell carcinoma;
unresectable;
conversion therapy;
conversion surgery;
review
- From:
Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
2024;31(07):1050-1057
- CountryChina
- Language:Chinese
-
Abstract:
Esophageal squamous cell carcinoma can easily penetrate into the esophageal wall and invade adjacent organs due to the lack of serosa. Stage cT4b tumors involving organs adjacent to the aorta, vertebral body, trachea, or bronchus were considered unresectable. For unresectable esophageal squamous cell carcinoma, radical chemoradiotherapy or chemotherapy is recommended. However, the therapeutic effect is poor. With the advent of conversion surgery, surgical resection is feasible after induction therapy for patients with esophageal tumors that are initially unresectable due to adjacent organ invasion or distant metastasis. This article reviews the research on conversion surgery for unresectable esophageal squamous cell carcinoma in recent years in order to explore the clinical application prospects of conversion surgery.
