Innovation of Methods for Efficacy Evaluation of Traditional Chinese Medicine Compound Prescriptions： Establishment of Characterization System for Simultaneous Treatment/Regulation Based on Correlation Patterns of Five Zang-organs
10.13422/j.cnki.syfjx.20250393
- VernacularTitle:符合中医药特点的中药药效评价创新方法： 基于五脏关联规律的中药复方“同治/同调”药效优势表征体系构建思考
- Author:
Yujie LI
1
;
Tuo LIU
2
;
Luqi WANG
1
;
Lina CHEN
2
;
Yan LIANG
1
;
Chengcheng LIU
1
;
Yu LI
1
;
Xiaoxin ZHU
1
Author Information
1. State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs，Institute of Chinese Materia Medica，China Academy of Chinese Medical Sciences，Beijing 100700，China
2. Artemisinin Research Center，China Academy of Chinese Medical Sciences，Beijing 100700，China
- Publication Type:Journal Article
- Keywords:
efficacy evaluation of traditional Chinese medicine;
theory of Zangxiang;
five Zang-organs;
simultaneous treatment;
heart-lung correlation
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2024;30(23):19-26
- CountryChina
- Language:Chinese
-
Abstract:
The clinical efficacy advantages of traditional Chinese medicine （TCM） compound prescriptions have always been inadequately characterized in experimental research，which has become a bottleneck restricting the development of TCM pharmacology and even the progress of TCM. The concept of simultaneous treatment/regulation，guided by the theory of mutual generation and restriction of five zang-organs，has guiding significance in the clinical practice of TCM throughout history and is still widely used in the current clinical practice. However，this unique and clinically valuable diagnostic and therapeutic medication system based on the syndrome differentiation has been completely ignored in the modern research of TCM pharmacology，which might be one of the key factors restricting the pharmacological characterization of the therapeutic advantages of TCM compound prescriptions. On the basis of systematically summarizing the phased progress and achievements of the efficacy evaluation of TCM compound prescriptions，this article explores the path of exploring the pharmacological advantages of TCM compound prescriptions on simultaneous treatment/regulation on the basis of the correlation patterns of five zang-organs，from the theory of Zangxiang，the core concept of five zang-organs，and the TCM disease recognition based on the theory of mutual generation and restriction of five zang-organs. With the heart-lung correlation as a breakthrough point，this study explored a new characterization method for the pharmacological advantages of TCM，aiming to provide new ideas for evaluating the efficacy of TCM compound prescriptions.
