Sesquiterpenoid glycosides from the aerial parts of Sarcandra glabra
10.11665/j.issn.1000-5048.2024052203
- VernacularTitle:草珊瑚地上部分倍半萜苷类成分研究
- Author:
Qianqian LI
1
;
Nan WANG
;
Jun LUO
Author Information
1. 中国药科大学中药学院
- Publication Type:Journal Article
- Keywords:
Chloranthaceae / Sarcandra glabra / glycoside / phenolic acids / chemical constituents
- From:
Journal of China Pharmaceutical University
2024;55(5):639-644
- CountryChina
- Language:Chinese
-
Abstract:
In order to explore the chemical constituents of Sarcandra glabra (Thunb.) Nakai, 10 compounds were isolated and identified from the water extraction of fresh aerial parts of Sarcandra glabra by silica gel column chromatography, polyamide column chromatography, gel column chromatography, and preparative high-performance liquid chromatography, including 2 elemane-type sesquiterpenoid glycosides, 6 violet ketone sesquiterpenoid glycosides, and 2 phenolic acid compounds. Based on their physicochemical properties and NMR data, the above compounds have been identified as sarcaglaboside C (1), sarcaglaboside D (2), byzantionoside B (3), lauroside E (4), (4Z)-4-[(3S)-3-(β-D-glucopyranosyloxy)butylidene]-3,5,5-trimethyl-2-cyclohexen-1-one (5), dihydrovomifoliol-O-β-D-glucopyranoside (6), (+)-abscisyl-β-D-glucopyranoside (7), 9ξ-O-β-D-glucopyranosyloxy-5-megastigmen-4-one (8), rosmarinic acid methyl ester (9) and methyl isorinate (10). Among them, compounds 3 - 5 and 8 - 9 were firstly isolated from S. glabra. The discovery of these compounds further enriches the structural types of compounds in S. glabra plants and provides an important material basis for subsequent pharmacological activity research.
