Drug delivery strategies and clinical research progress for encephalopathy
10.11665/j.issn.1000-5048.2024063001
- VernacularTitle:脑病用药递送策略及临床研究进展
- Author:
Ningshu LU
1
;
Tao JI
;
Yinglan LU
;
Xiyuan XU
;
Xiaochen GU
;
Yang DING
Author Information
1. 中国药科大学药剂系
- Publication Type:Journal Article
- Keywords:
drug for encephalopathy / drug delivery / blood-brain barrier / development strategy / clinical progresses
- From:
Journal of China Pharmaceutical University
2024;55(5):577-589
- CountryChina
- Language:Chinese
-
Abstract:
The blood-brain barrier in humans significantly restricts the effective delivery of drugs into the brain, resulting in poor therapeutic efficacy and difficulty in brain disease management. In recent years, innovative strategies and novel preparations have been studied and developed in order to circumvent the blood-brain barrier, achieve efficient drug entry into the brain, minimize the incidence of peripheral adverse effects, and bring significant therapeutic outcomes to patients. This review summarizes some key development strategies for treating encephalopathy, to provide some insights for the development of the next generation of drugs.
