Research progress on resistance mechanisms of carbapenem-resistant Enterobacteriaceae

VernacularTitle:耐碳青霉烯类肠杆菌耐药机制的研究进展
Author: Shuyu QIAN ¹ ; Tiejun LI
Author Information

1. 上海交通大学医学院附属仁济医院浦南分院药剂科,上海 200125
Keywords: carbapenem-resistant Enterobacteriaceae; mechanisms of drug resistance; anti-infective treatment
From: Journal of Pharmaceutical Practice and Service 2024;42(10):419-425
CountryChina
Language:Chinese
Abstract: Carbapenem-resistant Enterobacteriaceae(CRE)is an increasingly serious threat to human health worldwide.CRE usually carries multiple drug resistance genes,which limit the selection of therapeutic drugs,prolong treatment time,require higher treatment costs and greater treatment risks.The epidemiology,resistance mechanisms,current resistance status of CRE and the latest therapeutic drugs for CRE were summarized in this papoer,which provide a basis for the rational use of antibiotics in clinical prevention and treatment of drug-resistant bacterial infections.