Meta-analysis of diagnostic value of the axial length/corneal radius of curvature in children and adolescents with myopia
10.3980/j.issn.1672-5123.2024.11.19
- VernacularTitle:眼轴长度与角膜曲率半径比值对儿童青少年近视诊断价值的Meta分析
- Author:
Piao JIANG
1
;
Lixia ZHANG
1
;
Leiyan SU
1
;
Lixia ZHANG
1
;
Mengying TANG
1
;
Shuang CHEN
1
Author Information
1. Eye Hospital, China Academy of Chinese Medical Sciences, Beijing 100040, China
- Publication Type:Journal Article
- Keywords:
myopia;
axial length/corneal radius of curvature(AL/CR);
children and adolescents;
diagnostic tests;
Meta-analysis
- From:
International Eye Science
2024;24(11):1795-1801
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the diagnostic value of the axial length/corneal radius of curvature(AL/CR)for myopia in children and adolescents.METHODS: PubMed, Embase, The Cochrane Library, CNKI, CBM, WanFang Data and VIP databases were searched to collect clinical research on the value of AL/CR in diagnosing myopia in children and adolescents, and the retrieval time was from establishment to September 30, 2023. The QUADAS-2 tool was used to evaluate the quality of the extracted literature. A random-effects model was used to pool diagnostic test data, Meta-regression and subgroup analysis were performed to explore sources of heterogeneity.RESULTS: A total of 10 articles involving 19 872 study participants were included, and Meta-analysis showed that the pooled sensitivity of the AL/CR for the diagnosis of myopia in children and adolescents was 0.91[95%CI(0.90-0.91)], the pooled specificity was 0.84 [95%CI(0.84-0.85)], and area under the SROC curve of 0.95 [95%CI(0.93-0.96)].CONCLUSION: The AL/CR is a good indicator of myopia in children and adolescents.
