Research progress in clinical reuse of small incision lenticule extraction-derived lenticule
10.3980/j.issn.1672-5123.2024.11.13
- VernacularTitle:SMILE来源的角膜基质透镜临床再利用的研究进展
- Author:
Qing HUANG
1
;
Yixia ZHANG
1
;
Qian JIAN
1
Author Information
1. Department of Refractive Surgery, Chongqing Nanping Aier Eye Hospital, Chongqing 400060, China
- Publication Type:Journal Article
- Keywords:
small incision lenticule extraction(SMILE);
corneal stroma lenticule;
reuse;
corneal ulcer perforation;
hyperopia;
presbyopia
- From:
International Eye Science
2024;24(11):1759-1763
- CountryChina
- Language:Chinese
-
Abstract:
With the popularization of small incision lenticule extraction(SMILE), a large number of one-piece corneal stromal lenticules are removed during surgery. As an additional product of surgery, the experimental research and clinical reuse of extracted corneal stromal lenticules from SMILE have become a research hotspot in recent years. Corneal stromal lenticules are thin and transparent, rich in sources, low in cost, and have the advantages of low immunogenicity and good tissue compatibility, so they can be used as important source of cells and corneal stroma research, and also can be used as good biomaterials for corneal reinforcement, patch graft, refractive correction, and lacrimal duct embolization in clinical study. This article reviews the clinical application of SMILE-derived lenticule in the treatment of corneal-related diseases, correction of hyperopia and presbyopia, coverage of glaucoma drainage valve to prevent their exposure, and its use in lacrimal duct plug, aiming to fully recognize the reuse of lenticules in clinical practice, expand its surgical indication, and providing new directions for the treatment of other eye diseases and its application in tissues and organs.
