The Survival and Associated Factors for Patients on Peritoneal  Dialysis With History of Admission From Volume Overload

Jaruwan Thuanman; Pornpen Sangthawan; Kavin Thinkhamrop; Bandit Thinkhamrop; Jadsada Thinkhamrop; Siribha Changsirikulchai

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The Survival and Associated Factors for Patients on Peritoneal Dialysis With History of Admission From Volume Overload

Author: Jaruwan Thuanman ^{1
,

2} ; Pornpen Sangthawan ³ ; Kavin Thinkhamrop ⁴ ; Bandit Thinkhamrop ^{1
,

2} ; Jadsada Thinkhamrop ⁵ ; Siribha Changsirikulchai ⁶
Author Information

1. Epidemiology and Biostatistics Program, Faculty of Public Health, Khon Kaen University, Khon Kaen 40002, Thailand&
2. Data Management and Statistical Analysis Center (DAMASAC), Faculty of Public Health, Khon Kaen University, Khon Kaen 40002, Thailand
3. Division of Nephrology, Department of Medicine, Faculty of Medicine, Prince of Songkla University, Songkhla 90110, Thailand
4. Health and Epidemiology Geoinformatics Research (HEGER), Faculty of Public Health, Khon Kaen University, Khon Kaen 40002, Thailand
5. Department of Obstetrics and Gynecology, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand
6. Division of Nephrology, Department of Medicine, Faculty of Medicine, Srinakharinwirot University, Nakhonnayok 26120, Thailand
Publication Type:Journal Article
Keywords: Dialysis, kidney replacement therapy, patient survival, peritoneal dialysis, volume overload
From:Malaysian Journal of Medicine and Health Sciences 2024;20(No.2):11-17
CountryMalaysia
Language:English
Abstract: Introduction: Patients with peritoneal dialysis (PD) who develop volume overload (VO) have high risks of dropout from death or advancement to hemodialysis. We aimed to determine the mortality rates, associated factors, and patient survival rates of PD patients who had history of admission from VO. Methods: We reviewed data of PD patients who were registered in the Database of Peritoneal dialysis in EXcel (DPEX) from January 2008 to December 2018. They were followed until death or the end of June 2020. Patients with at least 18 years of age and history of admission from VO were classified into two groups. Group A had a history of VO after starting PD. Group B had a history of VO before and after starting PD. The mortality rates were calculated. Patient survival and associated factors were evaluated by Kaplan-Meier and multiple cox regression, respectively. Results: 1,882 patients had history of admission from VO. The overall mortality rate was 28.9 per 100 person-years. The mortality rates in group A and group B were 25.4 and 41.7 per 100 person-years, respectively. Patients in group A had lower age, fewer comorbidities, longer dialysis vintage, and better patient survival than those in group B. Factors related to worsening patient survival were increased age, diabetes, and comorbidities. Conclusion: Patients with history of admission from VO before and after the start of PD had higher mortality rates than those with history of admission from VO after PD. Increased age, diabetes, and comorbidities were the associated factors of patient survival.
Full text:202410211047281384311.2024my1760.pdf