Epidemiological investigation of a human adenovirus infection outbreak in a kindergarten
10.19485/j.cnki.issn2096-5087.2024.10.015
- Author:
XIE Cifu
;
XIONG Zi
;
SONG Lixin
;
YIN Pengliang
- Publication Type:Journal Article
- Keywords:
human adenovirus;
outbreak;
kindergarten;
epidemiological investigation
- From:
Journal of Preventive Medicine
2024;36(10):889-892
- CountryChina
- Language:Chinese
-
Abstract:
Abstract:On May 30 2022, Changsha Center for Disease Control and Prevention received a report of multiple cases of fever from a kindergarten. A field epidemiology investigation, laboratory testing, and control and prevention work were immediately conducted. A total of 76 cases were reported, and all were students, with an attack rate of 9.93%. The onset of illness was peaked between May 18 and June 8. The main clinical symptoms were fever, cough and sore throat, and all the cases were mild. There were 39 cases tested positive for human adenovirus (HAdV) nucleic acid or antigen, and 7 nucleic acid positive specimens were identified as HAdV-7 through virus isolation, culture and genotyping. The field epidemiology investigation and laboratory testing results concluded that it was a clustered outbreak caused by HAdV-7 infection. The main reason for the spread of the outbreak might be that the kindergarten failed to report it in time. High student density, poor classroom ventilation, lax morning and afternoon inspections, non-standard daily disinfection, and the prevalence of HAdV outbreaks in the community were also associated. Kindergartens should improve its infectious disease prevention and control mechanism, strictly follow the reporting regulations, implement the three early measures, standardize disinfection work, and enhance daily ventilation to avoid similar outbreaks in the future.
- Full text:2024101613260833977一起幼儿园人腺病毒感染暴发疫情流行病学调查.pdf