Role of regulated cell death in the development of gastric cancer
10.12025/j.issn.1008-6358.2024.20240346
- VernacularTitle:调节性细胞死亡在胃癌发生发展中的作用
- Author:
Yang YU
1
;
Yun XU
1
;
Jingyuan CAO
1
;
Junling HAN
1
;
Chenglin ZHOU
1
Author Information
1. Department of Laboratory Medicine, the Affiliated Taizhou People’s Hospital of Nanjing Medical University, Taizhou 225300, Jiangsu, China.
- Publication Type:Review
- Keywords:
gastric cancer;
regulated cell death;
apoptosis;
pyroptosis;
ferroptosis;
cuproptosis;
autophagy
- From:
Chinese Journal of Clinical Medicine
2024;31(4):652-658
- CountryChina
- Language:Chinese
-
Abstract:
Gastric cancer is one of the most common malignant tumors worldwide, with its incidence and mortality rates ranking third among malignant tumors in China. Regulated cell death (RCD) is a type of cell death activated by signal transduction modules and closely connected to the progression and treatment of gastric cancer. Different types of RCD, comprising apoptosis, pyroptosis, ferroptosis, cuproptosis, and autophagy, not only aid in eliminating damaged cells, but also serve a crucial role in suppressing gastric cancer spread. This paper reviews different forms of RCD and their roles in the progression of gastric cancer, so as to provide reference for new diagnosis and treatment strategies of gastric cancer.
