Clinical profile and management approach of patients diagnosed with resistant hypertension in the Philippine General Hospital
- Author:
Gelza Mae A. Zabat
1
;
Janellen L. Quiambao
1
;
Ela C. Villaverde
1
;
Christine Lorraine D. Balibadlan
1
;
Raymond V. Oliva
2
Author Information
- Publication Type:Journal Article
- Keywords: elevated blood pressure; resistant hypertension
- MeSH: Drug Combinations; Hypertension
- From: Philippine Journal of Cardiology 2023;51(1):85-91
- CountryPhilippines
- Language:English
-
Abstract:
INTRODUCTION:Resistant hypertension is blood pressure (BP) that remains above target despite treatment with maximum doses of three antihypertensive drugs, which may include a diuretic. The prevalence of resistant hypertension is unknown, and there are no local studies in the Philippines concerning this condition.
METHODS:A retrospective descriptive cohort study was conducted in the Hypertension Clinic of the Section of Hypertension of the Philippine General Hospital. A total of 51 patients were diagnosed with resistant hypertension, and charts were reviewed and analyzed.
RESULTS:Majority of the patients were female (31 [60.8%]), with a mean age of 56.3 years. All of them presented with symptoms; the most common presenting symptoms were headache, exertional dyspnea, nape pain, dizziness, and easy fatigability. Of the 51 patients, 45% also had diabetes mellitus, 11.8% had dyslipidemia, and 7.8% had a previous history of preeclampsia. Approximately 35% of these patients were smokers. The average BP before referral to the section was 167/94 mm Hg. By this time, most patients will either be on a four-drug regimen (42.1%) or a three-drug regimen (36.8%). The median number of visits in the Hypertension Clinic before control of BP was three follow-ups, with the average BP being 119/71 mm Hg. The regimens of the patients with controlled BP are three-drug combination (36.4%), four-drug combination (36.4%), and five-drug combination (27.3%).
CONCLUSION:Early referral to a hypertension specialist may benefit a patient with resistant hypertension, decreasing the number of follow-up visits to control a patient’s BP. Patients with resistant hypertension may require four- to five-drug regimens, which may be needed to adequately control a patient’s BP. - Full text:202410141015169856385_PJC Jan-Jun 2023PJC Vol 51 No 1 final.pdf
