Pulmonary tumor thrombotic microangiopathy in a patient with breast cancer.
- Author:
Jeong Hwan YOO
1
;
Yong Hun KIM
;
Dae Young KIM
;
Hae Youn KANG
;
In Jai KIM
;
Sang Wook LIM
;
Dong Hoon CHA
Author Information
1. Department of Internal Medicine, Bundang CHA Hospital, College of Medicine, Pochon CHA University, Seongnam, Korea.
- Publication Type:Case Report
- Keywords:
Pulmonary tumor thrombotic microangiopathy;
Pulmonary hypertension;
Breast cancer
- MeSH:
Ants;
Arterioles;
Blood Vessels;
Breast;
Breast Neoplasms;
Dyspnea;
Female;
Heart Failure;
Humans;
Hypertension, Pulmonary;
Middle Aged;
Pulmonary Artery;
Thrombotic Microangiopathies
- From:Korean Journal of Medicine
2009;76(Suppl 1):S87-S92
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Pulmonary tumor thrombotic microangiopathy (PTTM) is a rare malignancy-related complication causing severe pulmonary hypertension, right heart failure, and death. PTTM is characterized by diffuse fibrocellular intimal proliferation and multiple thrombi formation in the pulmonary arteries and arterioles, which result from invasion of the pulmonary blood vessels by tumor cells. Establishing the diagnosis of PTTM is very difficult and few cases are diagnosed ante mortem. We report the case of a 48-year-old woman diagnosed with PTTM before death who developed breast cancer and presented with persistent dyspnea on exertion.
