A case of Wegener's granulomatosis masquerading as a lung abscess.
- Author:
Hye Ok KIM
1
;
Ki Hwan JUNG
;
Je Hyeong KIM
;
Hyung Joo PARK
;
Young Sik KIM
;
Chol SHIN
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Ansan Hospital, Ansan, Korea.
- Publication Type:Case Report
- Keywords:
Wegener's granulomatosis;
Interstitial lung disease;
Antineutrophil cytoplasmic antibody
- MeSH:
Antibodies, Antineutrophil Cytoplasmic;
Cytoplasm;
Early Diagnosis;
Fever;
Glycosaminoglycans;
Hematuria;
Humans;
Inflammation;
Kidney;
Lung;
Lung Abscess;
Lung Diseases, Interstitial;
Middle Aged;
Otitis Media;
Prognosis;
Respiratory System;
Thorax;
Vasculitis;
Wegener Granulomatosis
- From:Korean Journal of Medicine
2009;76(Suppl 1):S97-S102
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Wegener's granulomatosis is a small vessel vasculitis characterized by necrotizing granulomatous inflammation of the upper and lower respiratory tracts and kidney. Early diagnosis and immediate treatment are very important for a better prognosis, but the nonspecific, variable clinical manifestations and radiologic findings make the diagnosis difficult. A positive proteinase 3-antineutrophil cytoplasmic antibody test is helpful for the diagnosis of Wegener's granulomatosis. Here, we report a case of Wegener's granulomatosis in 54-year-old man who initially presented with fever and multiple cavitary consolidations on the chest radiograph suggestive of a lung abscess. The final diagnosis of Wegener's granulomatosis was based on the medical history of otitis media, gradually developed microscopic hematuria, necrotizing granulomatous inflammation on lung histopathology, and a positive proteinase 3-antineutrophil cytoplasmic antibody test.
