Research progress on toxic effects of vanadium and its compounds

Author: LI Jiaping ; JIANG Zhaoqiang ; LI Tao
Publication Type:Journal Article
Keywords: vanadium; toxic effect; oxidative stress; DNA damage; mechanism
From: Journal of Preventive Medicine 2024;36(9):772-775,780
CountryChina
Language:Chinese
Abstract: Abstract:Vanadium is widely used in the steel manufacturing, aerospace and medical industries because of its good plasticity and malleability, and is released into the environment in large quantities. Human were exposed mainly through environmental and occupational exposure. Vanadium and its compounds can cause multi-system damage to the reproductive, respiratory, neurological, and immune systems, and the toxic mechanisms may be related to oxidative stress, epigenetic damage, DNA damage and repair, apoptosis, and dysregulation of cell proliferation. This article summarizes the health hazards caused by vanadium exposure and its mechanism, providing the reference for the studies into the toxic effects of vanadium and its compounds.
Full text:202410081103460214钒及其化合物毒性作用研究进展.pdf