Vitreoretinal Interface Changes In Type 2 Diabetic Retinopathy Based On Swept-source Optical Coherence Tomography/ Swept-source Optical Coherence Tomography Angiography
10.13471/j.cnki.j.sun.yat-sen.univ（med.sci）.20240907.005
- VernacularTitle:基于SS-OCT/SS-OCTA探究玻璃体视网膜界面改变对2型糖尿病视网膜病变的影响
- Author:
Peiyao LU
1
;
Ruoyu CHEN
2
;
Dan CAO
3
;
Liang ZHANG
3
Author Information
1. Guangdong Cardiovascular Institute//Guangdong Provincial People’s Hospital// Guangdong Academy of Medical Sciences， Guangzhou 510080， China
2. Guangdong Provincial People’s Hospital affiliated to South Medical University//South Medical University， Guangzhou 510080， China
3. Guangdong Provincial People’s Hospital//Guangdong Academy of Medical Sciences//Guangdong Cardiovascular Institute， Guangzhou 510080， China
- Publication Type:Journal Article
- Keywords:
swept-source optical coherence tomography / swept-source optical coherence tomography angiography;
diabetic retinopathy;
posterior vitreous detachment;
vitreoretinal adhesion;
vitreoretinal interface
- From:
Journal of Sun Yat-sen University(Medical Sciences)
2024;45(5):826-834
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo observe and analyze the vitreoretinal interface changes in type 2 diabetic retinopathy （DR） by using ultra-wide field swept-source optical coherence tomography （UWF SS-OCT） / swept-source optical coherence tomography angiography （SS-OCTA）. MethodsThis study enrolled 143 patient with diabetic mellitus. We performed SS-OCT on 258 eyes and OCTA on 69 eyes with proliferative diabetic retinopathy （PDR）， then analyzed the images to assess the relationship between posterior vitreous detachment （PVD） and DR severity， and to measure the growth of retinal neovascularization in PDR eyes with different stages of PVD. ResultsPVD stage was negatively correlated with DR severity （Gamma=-0.294， P< 0.001）， that is， the more extensive the vitreoretinal adhesion， the more severe the DR. The negative correlation between PVD stage and DR severity was more evident in patients with diabetes duration more than 10 years （Gamma=-0.620， P< 0.001）. Retinal neovascularization occurred more commonly in the area of vitreoretinal adhesion. ConclusionsThe degree of vitreoretinal adhesion is closely related to the DR severity. It is very important to use SS-OCT to evaluate the vitreoretinal interface in the management of DR patients.
