Influencing factors and epidemiological survey of diffuse toxic goiter with hyperthyroidism in Xining
10.3969/j.issn.1006-2483.2024.05.033
- VernacularTitle:西宁地区毒性弥漫性甲状腺肿甲状腺功能亢进症流行病学调查及影响因素
- Author:
Yonggui LI
1
,
2
;
Qinfang ZHU
1
,
2
;
Xiaoluan LI
1
,
2
;
Lingming ZHANG
1
,
2
Author Information
1. Department of Endocrinology , Qinghai Provincial People'
2. s Hospital , Xining , Qinghai 810007, China
- Publication Type:Journal Article
- Keywords:
Diffuse toxic goiter;
Hyperthyroidism;
Epidemiology;
Influencing factor
- From:
Journal of Public Health and Preventive Medicine
2024;35(5):138-141
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the epidemiological status of toxic diffuse goiter hyperthyroidism (abbreviated as hyperthyroidism) in Xining area and analyze its influencing factors. Methods Patients with toxic diffuse goiter and hyperthyroidism who were hospitalized in Class ⅲ Grade A hospitals in Xining from January 2020 to January 2023 were collected as the experimental group by random cluster sampling method. During the same period, 500 healthy people in each hospital were selected as the control group. The general data of the patients were collected and the levels of thyroid function indexes of the two groups were detected. Multivariate logistic regression was used to analyze the influencing factors of diffuse goiter with hyperthyroidism. Results A total of 718 questionnaires were collected in this study, and 705 questionnaires were collected after excluding invalid questionnaires. There were 234 males and 471 females in 705 patients with diffuse goiter and hyperthyroidism. The most common age was 41-50 years, followed by 51-60 years and 31-40 years. The serum TSH level of the experimental group was lower than that of the control group, and the levels of FT3 and FT4 were higher than those of the control group ( P < 0.05 ) . There was no significant difference in family history, thyroid texture and thyroid imaging between the two groups ( P > 0.05 ). There were significant differences in exophthalmos and thyroid weight between the two groups (P<0.05). Multivariate Logistic regression analysis showed that exophthalmos, thyroid weight ≥30g , TSH , FT3 and FT4 were independent risk factors for the experimental group ( P < 0.05) . Conclusion Gender, age, exophthalmos, thyroid weight and thyroid related hormone levels are the influencing factors of diffuse goiter and hyperthyroidism in Xining area . Thyroid function should be monitored for early prevention and treatment of the disease.
