Therapeutic effect of intraovarian injection of autologous platelet-rich plasma for the treatment of diminished ovarian reserve
10.13303/j.cjbt.issn.1004549x.2024.09.005
- VernacularTitle:自体富血小板血浆卵巢内注射治疗卵巢储备功能减退的疗效观察
- Author:
Hongbo WU
1
;
Yanmei LIU
1
;
Zhao ZHANG
1
;
Liling LIU
2
Author Information
1. Qinzhou Maternal and Child Health Hospital, Qinzhou 535000, China
2. Reproductive Medical and Genetic Center, The People’s Hospital of GuangXi Zhuang Autonomous Region
- Publication Type:Journal Article
- Keywords:
platelet-rich plasma(PRP);
diminished ovarian reserve(DOR);
assisted reproduction
- From:
Chinese Journal of Blood Transfusion
2024;37(9):998-1002
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To explore the effectiveness of intraovarian injection of platelet-rich plasma(PRP) in the treatment of patients with diminished ovarian reserve(DOR), aiming to provide new diagnostic and therapeutic ideas for the treatment. 【Methods】 A total of 22 patients with DOR who underwent autologous PRP ovarian injection at the Reproductive Medical and Genetic Center of Qinzhou Maternal and Child Health Hospital from January 2021 to December 2023 were collected. Among them, 12 patients underwent assisted reproductive technology for pregnancy. The patient′s anti-Müllerian hormone (AMH), antral follicle count (AFC), basal follicle-stimulating hormone (FSH), basal luteinizing hormone (LH) and basal estradiol (E2) levels were observed. 【Results】 The levels of AMH, AFC, basal FSH, basal LH and basal E2 in 22 patients improved after treatment compared with those before treatment. Of the 12 patients who received assisted reproduction, 2 had IVF cycle canceled due to poor ovarian reaction. Ten patients obtained embryos, of which 5 obtained high-quality embryos. 【Conclusion】 Intraovarian injection of autologous PRP can effectively improve ovarian reserve function in patients with DOR.
