New Combination Therapy for Vitiligo: An Effective and Short Term Regimen.
10.5021/ad.1995.7.3.231
- Author:
Hong Yong KIM
;
Soo Lieon PARK
- Publication Type:Original Article
- Keywords:
Combination therapy;
Vitiligo
- MeSH:
Adrenal Cortex Hormones;
Chlorpromazine;
Humans;
Methods;
Photochemotherapy;
Vitiligo*
- From:Annals of Dermatology
1995;7(3):231-235
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: The main therapeutic method currently used for the treatment of vitiligo vulgaris is either photochemotherapy or corticosteroids. But both of the procedures however require lengthy treatment to obtain a satisfactory result. OBJECTIVE: To determine the increased efficacy of the combination therapy of photochemotherapy with corticosteroid and chlorpromazine compared with the usual monotherapy. METHODS: The combination therapy was done in 29 cases and the results were compared with the results of either monotherapy appearing in the literatures. RESULTS: f the 29 patients, 14(48.3%) patients achieved 100% repigmentation, 7(24.1%) patients 75~50%, 5(17.2%) patients 25~50%, and 3(10.4%) patients less than 25%. For the cured patients, 190.3 days and 32.7 times of photochemotherapy were used. CONCLUSION: The combination therapy is more effective, and the duration of treatment can be greatly reduced compared with either monotherapy.
