Application of indocyanine green fluorescence imaging in the precise dissection of lymph nodes during laparoscopic radical resection of bladder cancer
10.3969/j.issn.1009-8291.2024.07.015
- VernacularTitle:吲哚菁绿荧光显像在腹腔镜膀胱癌根治术淋巴结精准清扫中的应用
- Author:
Lifeng LIU
1
;
Yansong GUO
1
;
Hao WANG
1
;
Xiaopeng WANG
1
;
Fengshuo YANG
1
;
Yuepeng HU
1
;
Longjiang TIAN
1
Author Information
1. Department of Urology, Cangzhou People’s Hospital, Cangzhou 061000, China
- Publication Type:Journal Article
- Keywords:
muscular invasive bladder cancer;
indocyanine green;
pelvic lymph node dissection;
radical cystectomy
- From:
Journal of Modern Urology
2024;29(7):638-641
- CountryChina
- Language:Chinese
-
Abstract:
【Objective】 To investigate the efficacy, safety and feasibility of laparoscopic lymph node dissection guided by indocyanine green (ICG) fluorescence imaging. 【Methods】 A total of 30 patients with muscle-invasive bladder cancer (MIBC, T2/T3NxM0) who were admitled to the Cangzhou People’s Hospital during Mar.2018 and Jun.2022 were included.The lymph nodes were cleared with ICG fluorescence imaging first, and then the remaining lymph nodes were cleared according to the standard pelvic lymph node range.The lymph node positive rate of ICG fluorescence imaging guided laparoscopic lymph node precise dissection and standard pelvic lymph node dissection was analyzed by self-comparison. 【Results】 ICG fluorescence imaging guided laparoscopic lymph node precise dissection needed shorter operation time than standard pelvic lymph node dissection \[(21.80±6.80) min vs.(47.70±10.73) min, P<0.05\].There was no significant difference in the lymph node positive rate between the two approaches \[(11.34±9.06)% vs. (12.36±9.43)%, P>0.05\], but the former approach caused less damage on blood vessels and nerves. 【Conclusion】 Indocyanine green fluorescence imaging guided laparoscopic lymph node dissection has comparable efficacy to standard pelvic lymph node dissection, which can reduce ineffective lymph node dissection, shorten the operation time, and reduce the risk of complications.
