Robot-assisted urinary control recovery and safety assessment of vesicoprostatic muscle reconstruction after extubation in patients undergoing radical prostatectomy for prostate cancer:a prospective randomized controlled trial
10.3969/j.issn.1009-8291.2024.07.014
- VernacularTitle:膀胱前列腺肌重建的机器人辅助前列腺癌根治术患者拔管后尿控恢复及安全性评估:一项前瞻性随机对照试验
- Author:
Yueqi WU
1
,
2
;
Xuefei DING
;
Yang LUAN
;
Liangyong ZHU
;
Xiao TAN
;
Zhenhao WU
Author Information
1. 扬州大学医学院研究生院,江苏扬州 225100
2. 扬州大学附属苏北人民医院泌尿外科,江苏扬州 225001
- Keywords:
robotic-assisted;
radical prostatectomy;
vesicoprostatic muscle;
urinary control;
overlapping weighting
- From:
Journal of Modern Urology
2024;29(7):632-637,653
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the effects of vesicoprostatic muscle(VPM)reconstruction on the early urinary control recovery and safety of patients undergoing robot-assisted radical prostatectomy(RARP).Methods A total of 128 patients who underwent RARP in our hospital during Sep.1,2021 and Aug.31,2023 were enrolled and divided into the non-reconstruction group(n=64)and reconstruction group(n=64)using random number table method.The reconstruction group received Montsouris+VPM reconstruction surgery,while the non-reconstructive group underwent Montsouris surgery only.Urinary control and perioperative data were collected with telephone interview,outpatient follow-up and inpatient records.The two groups were matched using overlap weighting and the Kaplan-Meier method was used to calculate urinary incontinence rates at 1,2 and 3 months after extubation.Early urinary control(3 months after extubation),operation time,intraoperative bleeding,positive rate of incision margin,and incidence of early postoperative complications(<30 days)(Clavien-Dindo scale)were compared between the two groups.Results The recovery rate of urinary control at 1,2 and 3 months after extubation was significantly higher in the reconstruction group than that in the non-reconstruction group(33.9%vs.11.2%;46.7%vs.16.1%;70.6%vs.45.6%,P<0.05),but the positive rate of resection margin was lower(16.1%vs.41.7%,P<0.05).There were no significant differences in operation time,intraoperative bleeding and early postoperative complications between the two groups(P>0.05).Conclusion VPM reconstruction can improve urinary control recovery in RARP patients early after extubation without increasing the risk of surgery.