Comparison of different laparoscopic treatments for upper urinary tract urothelial carcinoma
10.3969/j.issn.1009-8291.2024.07.007
- VernacularTitle:不同腹腔镜术式治疗上尿路尿路上皮癌的临床疗效比较
- Author:
Meng ZHU
1
;
Junfei GU
;
Yuepeng LIU
;
Zihao LI
;
Chao MA
;
Lixin REN
Author Information
1. 河北医科大学第二医院泌尿外科,河北石家庄 050000
- Keywords:
peritoneolaparoscopic single position nephreteral total length resection;
posterior laparoscopic subabdominal incision technique;
upper tract urothelial carcinoma
- From:
Journal of Modern Urology
2024;29(7):597-601
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the clinical efficacy of peritoneolaparoscopic single position nephreteral total length resection(PSPNTLR)and posterior laparoscopic subabdominal incision technique(PLSIT)in the treatment of upper urothelial carcinoma(UTUC).Methods A total of 82 UTUC patients treated in our hospital during Jan.2018 and Feb.2021 were divided into the observation group(n=41,treated with PSPNTLR)and control group(n=41,treated with PLSIT)according to the random number table method.Perioperative indicators,pain degree,inflammatory factors,bladder recurrence and distant metastasis were compared between the two groups.Results The operation time[(122.15±15.14)min vs.(160.88±17.26)min],hospitalization time[(10.07±2.14)d vs.(12.22±3.13)d]and postoperative exhaust time[(1.46±0.57)d vs.(3.10±0.88)d]were significantly shorter,the intraoperative blood loss[(42.85±4.88)mL vs.(78.22±8.17)mL]and drainage volume[(53.61±9.74)mL vs.(81.56±11.06)mL]were significantly less in the observation group than in the control group(P＜0.05).The visual analogue score(VAS)of the observation group at 6,12 and 24 h after operation was significantly lower than that of the control group(P＜0.05).The levels of interleukin-6(IL-6)and C-reactive protein(CRP)were increased in both groups one day after surgery,but the indexes were increased more significantly in the control group(P＜0.05).During the 2-year follow-up after surgery,there were no statistical difference in bladder recurrence(12.20％vs.14.63％)and distant metastasis(9.76％vs.4.88％)between the two groups(P＞0.05).Conclusion Both PSPNTLR and PLSIT have good therapeutic safety,but PSPNTLR is more effective in improving perioperative indicators,reducing postoperative pain,and inhibiting inflammatory factors.
